No, not really; the only issues are because Yoyo Games doesn't officially support Studio 1 anymore (despite having sold permanent licenses to the software), and tries to sell you Studio 2/newer versions of their IDE whenever possible. When I switched to a new laptop earlier this year, that made getting the software on my new computer/getting it to recognize my license more difficult. The program itself worked fine though! That said, I recently switched to Godot for any future projects, more out of a desire to avoid using Yoyo's dev tools in the future than anything else.