Clara for Genomics

Power unprecedented speed and accuracy in precision genomics with the NVIDIA Clara™ for Genomics software suite.

Why Clara for Genomics?

For Enterprise

Substantially reduce time to discovery and treatment identification with optimized workflows.

For IT

Transform time-consuming analysis from days to minutes to revolutionize the speed, accuracy, and throughput of genomic workflows.

For Developer

Optimize the alignment, processing, and variant calling of whole genomes and exomes for both germline and somatic workflows.

Accelerate Genomic Analysis From End to End

The genomics market encompasses various methods that cover wide-ranging applications across drug discovery, precision medicine, population health studies, and clinical diagnostics. The landscape is diverse, and includes research institutions, healthcare facilities, sequencing diagnostic centers, national programs, pharmaceuticals, and techbios—all of which play an essential role in genomics discoveries. Faster analysis leads to quicker diagnosis, personalized treatments, and streamlined drug discovery, saving time and resources while improving patient care and enabling real-time, data-driven decisions.

Accelerated Short-Read Analysis

Short-read sequencing generates short DNA sequences and is valued for its speed and affordability. NVIDIA® Parabricks® accelerates gold-standard secondary analysis tools, from alignment through variant calling, enabling rapid analysis of short-read sequencing data. These tools can be used with data from Element, Illumina, MGI, Singular, Thermo Fisher, and Ultima sequencers.

Accelerated Long-Read Analysis

Long-read sequencing is instrumental in identifying structural variants and can be used to assemble genomes from multiple samples, which can drive the study of genetic diversity in populations. NVIDIA Parabricks accelerates gold-standard secondary analysis tools for basecalling, alignment, and variant calling, enabling rapid analysis of long-read sequencing data. These tools can be used on data from Oxford Nanopore and PacBio long-read sequencers.

Single Cell

NVIDIA RAPIDS™ accelerates single-cell workflows for data processing and visualization, with a similar usability model as scverse Python libraries. cunnData provides a minimized, lightweight version of the AnnData object for the GPU, enabling rapid data manipulation and processing, which RAPIDS cuGraph and cuML libraries can then analyze downstream.

Product Suite

NVIDIA Parabricks

NVIDIA Parabricks provides GPU-accelerated versions of tools used every day by computational biologists and bioinformaticians—enabling significantly faster runtimes, workflow scalability, and lower compute costs.

NVIDIA Parabricks

NVIDIA Parabricks provides GPU-accelerated versions of tools used every day by computational biologists and bioinformaticians—enabling significantly faster runtimes, workflow scalability, and lower compute costs.

RAPIDS

RAPIDS is a suite of open-source libraries that can speed up end-to-end data science workflows through the power of GPU acceleration. RAPIDS makes it possible to perform interactive data analysis on large datasets using Python APIs.

Getting Started With NVIDIA Parabricks

NVIDIA Parabricks is available as a set of containers and pretrained models on NVIDIA NGC™ and DGX™ Cloud. Purchase of NVIDIA AI Enterprise comes with full access to enterprise support, including guaranteed response times, priority security notifications, and access to Parabricks experts.

Making a Real-World Impact

The Broad Institute

NVIDIA is collaborating with Broad to bring GPU-accelerated Parabricks to the Terra Platform, in addition to optimizing AI-accelerated workflows and large language models to advance discovery.

National Biobank of Thailand (NBT)

NBT reduced its whole-genome sequencing data processing by four months and its individual user processing time from over 30 hours to just 1–2 hours with NVIDIA DGX A100 and NVIDIA Parabricks.

The Human Genome Center (HGC)

HGC at the University of Tokyo announced a new genomics platform to accelerate genomic analysis by 40X compared to a CPU-based environment, utilizing NVIDIA Parabricks Pipelines genomics software.

Regeneron Genetics Center

Regeneron is using DeepVariant with NVIDIA Parabricks to generate scalable, high-quality data that can be reproduced across the genomics community.

Ultima

Ultima Genomics is collaborating with NVIDIA to deliver $100 genome sequencing with AI and accelerated computing.

Singular

Singular Genomics is collaborating with NVIDIA to deliver market-leading, next-generation sequencing and analysis speeds.

Oxford Nanopore

Oxford Nanopore is upgrading ‌its PromethION compute tower from NVIDIA V100 Tensor Core GPUs to A100 Tensor Core GPUs. This processing power increase will enable it to keep up with high-accuracy basecalling and greatly expand the capacity for super-accurate algorithms.

Image credit: Steve Fisch, courtesy of Stanford University.

Guinness World Record

A team of researchers achieved a new DNA sequencing record—five hours and two minutes—which will allow clinicians to draw blood from a critical-care patient and reach a genetic disorder diagnosis the same day.

Stanford University, Google, and Oxford Nanopore

Stanford has demonstrated huge reductions in runtime by integrating the GPU-accelerated implementation of DeepVariant available with NVIDIA Parabricks.

Purdue University

Researchers at Purdue completed a study that evaluates the performance and accuracy of a GPU-accelerated compute framework for pathogen genomic variant identification.

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