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Parkinson's & Movement disorders news
Genetics
Researchers identify new mutation in gene linked to amyotrophic lateral sclerosis
Researchers have identified a new mutation in the ARPP21 gene that could be the cause of amyotrophic lateral sclerosis (ALS), a devastating neurodegenerative disease. The researchers are from the Neuromuscular Diseases Group ...
10 hours ago
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Neuroscience
Molecular insights into cognitive impairment: New research uncovers how Parkinson's affects the brain
Parkinson's is associated with a higher risk of cognitive impairment and dementia that can severely impact quality of life. Cognitive symptoms include deficits in attention and mental flexibility, among others, and can pre-date ...
Jul 11, 2024
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Major trial looks at most effective speech therapy for people with Parkinson's disease
A major clinical trial, led by researchers at the University of Nottingham, has shown the Lee Silverman Voice Treatment (LSVT LOUD) is more effective than the current speech and language therapy provided by the NHS, when ...
Jul 10, 2024
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Study reveals racial disparities in Huntington's disease diagnoses
Research led by UCLA Health reveals that Black patients with Huntington's disease in the U.S. and Canada received their diagnoses, on average, one year later compared to white patients after symptoms first appear.
Jul 10, 2024
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Improving measurement of Parkinson's disease severity with AI
Despite recent advancements in the treatment of Parkinson's disease, it remains a challenge to accurately measure the progression of symptoms in this neurological disorder. While noticeable symptoms like tremors, stiffness ...
Jul 9, 2024
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Could AI be the answer to early Parkinson's disease diagnoses?
Parkinson's disease is a significant health concern with profound impacts on individuals, the health care system and broader society. The current diagnosis model, which heavily relies on a medical professional interpreting ...
Jul 9, 2024
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Erasing 'bad memories' to improve long term Parkinson's disease treatment
Common treatments for Parkinson's disease can address short-term symptoms, but can also cause extensive problems for patients in the long run. Namely, treatments can cause dyskinesia, a form of uncontrollable movements and ...
Jul 8, 2024
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Structure, function of brain connectome tied to gray matter atrophy in Parkinson disease
For patients with mild Parkinson disease (PD), the structural and functional architecture of the brain connectome is associated with progression of gray matter (GM) atrophy, according to a study published online June 25 in ...
Jul 8, 2024
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Acupuncture aids sleep in patients with Parkinson disease
Acupuncture is associated with improved sleep quality in patients with Parkinson disease, according to a study published online June 26 in JAMA Network Open.
Jul 5, 2024
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Scientists may have discovered how to diagnose elusive neuro disorder
Progressive supranuclear palsy (PSP), a mysterious and deadly neurological disorder, usually goes undiagnosed until after a patient dies and an autopsy is performed. But now, UC San Francisco researchers have found a way ...
Jul 3, 2024
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Cracking the code for cerebellar movement disorders
The cerebellum is a region of the brain that helps us refine our movements and learn new motor skills. Patients and mouse models experience many kinds of abnormal movements when their cerebellum is damaged. They can have ...
Jul 3, 2024
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The path to Parkinson's disease: All roads lead to the nigrosome
The main neuropathological feature of Parkinson's disease is the loss of dopaminergic neurons in the substantia nigra pars compacta. Specifically, dopaminergic neurons in the ventral tier of the substantia nigra pars compacta, ...
New cellular mechanisms in Parkinson's disease discovered
A pair of recent studies led by Joseph Mazzulli, Ph.D., associate professor in The Ken & Ruth Davee Department of Neurology's Division of Movement Disorders, have uncovered previously unknown cellular mechanisms involved ...
Jul 1, 2024
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Visualizing core pathologies of Parkinson's disease and related disorders in live patients
In countries with an aging population, neurodegenerative disorders such as Parkinson's disease (PD) and dementia with Lewy bodies (DLB) are becoming more prevalent. These conditions, for which no definitive cure currently ...
Jun 28, 2024
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Brain connectivity on MRI predicts Parkinson's disease progression
The structural and functional organization of the brain as shown on MRI can predict the progression of brain atrophy in patients with early-stage, mild Parkinson's disease, according to a study published today in Radiology, ...
Jun 25, 2024
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New research links anxiety to higher Parkinson's risk in over-50s
The risk of developing Parkinson's is at least twice as high in people with anxiety compared to those without, finds a new study by UCL researchers.
Jun 24, 2024
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Newly discovered subtypes and sex differences give insight into molecular mechanisms of ALS
Amyotrophic lateral sclerosis, ALS for short, is a mysterious neurodegenerative disease that is almost always fatal. A consortium of researchers led by the Technical University of Munich (TUM) has systematically investigated ...
Jun 21, 2024
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Drugs for enlarged prostate may also protect against dementia with Lewy bodies
A new study suggests that certain drugs commonly used to treat enlarged prostate may also decrease the risk for dementia with Lewy bodies (DLB). This observational finding may seem surprising, but it mirrors previous work ...
Jun 19, 2024
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Diagnosing essential tremor after death helps families learn risk
A statistical tool designed to analyze 11 characteristics of postmortem brains reliably diagnosed a common neurodegenerative disease known as essential tremor (ET), a study led by researchers at UT Southwestern Medical Center ...
Jun 19, 2024
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Blood test could predict Parkinson's seven years before symptoms
A team of researchers, led by scientists at UCL and University Medical Center Goettingen, has developed a simple blood test that uses artificial intelligence (AI) to predict Parkinson's up to seven years before the onset ...
Jun 18, 2024
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